effect of vitamin d insufficiency treatment on fertility outcomes in frozen-thawed embryo transfer cycles: a randomized clinical trial
نویسندگان
چکیده
background: frozen- thawed embryo transfer is an essential part of art treatment and outcomes of this procedure are associated with several clinical factors. several studies have showed an increase level of ivf outcomes in women with sufficient vitamin d. objective: whether treatment of vitamin d insufficiency can improve pregnancy rates in frozen-thawed embryo transfer cycles. materials and methods: this is an interventional, randomized clinical trial. serum 25-(oh) vitamin d level of 128 women who had undergone ivf/icsi with cryopreservation of embryos was checked. one hundred fourteen infertile women with insufficient serum vitamin d (less than 30 ng/ml) were included in the study. fifty seven women were treated with supplementary vitamin d, 50000 iu weekly, for 6-8 weeks and fifty seven women were received no supplementation. one hundred six women completed frozen thawed embryo transfer cycles and included in the final analysis. primary and secondary outcomes were chemical and clinical pregnancy respectively. results: our study did not show any significant difference between vitamin d insufficient and treated women in term of chemical (29.40% vs. 29.10% respectively, p=1.00) or clinical (25.50% vs. 21.80% respectively, p=0.81) pregnancy rates. conclusion: vitamin d insufficiency treatment is not associated with higher pregnancy rate in frozen-thawed embryo transfer cycles
منابع مشابه
Effect of vitamin D insufficiency treatment on fertility outcomes in frozen-thawed embryo transfer cycles: A randomized clinical trial
BACKGROUND Frozen- thawed embryo transfer is an essential part of ART treatment and outcomes of this procedure are associated with several clinical factors. Several studies have showed an increase level of IVF outcomes in women with sufficient vitamin D. OBJECTIVE whether treatment of vitamin D insufficiency can improve pregnancy rates in frozen-thawed embryo transfer cycles. MATERIALS AND ...
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Effect of Progesterone Supplementation on Natural Frozen-Thawed Embryo Transfer Cycles: A Randomized Controlled Trial
BACKGROUND The transfer of cryopreserved embryos can be timed with ovulation in a natural cycle or after artificially preparing the endometrium with exogenous hormones. Progesterone is essential for the secretory transformation of the endometrium that permits implantation as well as maintenance of early pregnancy. The purpose of this study is to assess the effect of luteal phase supplementation...
متن کاملFrozen-thawed embryo transfer cycles
In order to reduce the chance of multiple pregnancy during in-vitro fertilisation (IVF)– embryo transfer treatment, there is an increasing trend towards transferring a lower number of embryos. Surplus good-quality embryos are then transferred in frozen-thawed embryo transfer (FET) cycles. The first pregnancy after FET was reported in 1983.1 It has been estimated that in IVF programmes in which ...
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Background: The aim of this prospective randomized clinical trial was to determine the optimal endometrial preparation protocol by comparing the clinical outcome of two methods of endometrial preparation in FET cycles, that is, oral estradiol and 17 β-estradiol transdermal patch. Materials and Methods: A total number of 90 patients were scheduled for FET. In the study group (n=45), 17-B estradi...
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عنوان ژورنال:
international journal of reproductive biomedicineجلد ۱۲، شماره ۹، صفحات ۵۹۵-۰
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